Research was carried out on the Diabetes Market in the South African Healthcare Industry. A thorough PESTLE (political, economic, social, technology, legislation, and environmental) analysis was established for South Africa. Market sizes for both the insulin and oral anti-diabetic drugs sectors were calculated for 2006 and forecasts were determined for the period 2006-2012. In addition, the market dynamics such as the industry challenges, market drivers, and market restraints were identified.